Product Datasheet
XPF Antibody
Catalog Number: 33545
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q92889
NCBI Gene ID: 2072
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human XPF.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- DNA repair endonuclease XPF; EC 3.1.-.-; DNA excision repair protein ERCC-4; DNA-repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total XPF protein.
- Background:
- Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link.
Brookman K.W., Mol. Cell. Biol. 16:6553-6562(1996).
Sijbers A.M., Cell 86:811-822(1996).
Cleaver J.E., Hum. Mutat. 14:9-22(1999).
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