Product Datasheet  
XPF Antibody  
Catalog Number: 33545  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: Q92889
    NCBI Gene ID: 2072
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthesized peptide derived from internal of human XPF.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500~1:3000

  • other_names:  
  • DNA repair endonuclease XPF; EC 3.1.-.-; DNA excision repair protein ERCC-4; DNA-repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein
  • Purification:  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity:  
  • The antibody detects endogenous levels of total XPF protein.
  • Applications:  
  • WB
  • Background:  
  • Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link.

    Brookman K.W., Mol. Cell. Biol. 16:6553-6562(1996).
    Sijbers A.M., Cell 86:811-822(1996).
    Cleaver J.E., Hum. Mutat. 14:9-22(1999).



 
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