Product Datasheet
WNT1 Antibody
Catalog Number: 33543
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P04628
NCBI Gene ID: 7471
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human WNT1.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- ONCOGENE INT1; wingless-type MMTV integration site family; member 1; INT1; Proto-oncogene protein Wnt-1 [Precursor]
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total WNT1 protein.
- Background:
- Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development.
van Ooyen A., EMBO J. 4:2905-2909(1985).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
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