Product Datasheet
CD40 Antibody
Catalog Number: 33507
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P25942
NCBI Gene ID: 958
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human CD40.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CD40 protein.
- Background:
- Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Carlos Reyes-Moreno, J. Biol. Chem., May 2007; 10.1074.
Hongwei Qin, Blood, Nov 2005; 106: 3114 - 3122.
Meera J. Nathan, J. Immunol., Jun 2004; 172: 6626 - 6633.
Clare C. Davies, Mol. Cell. Biol., Nov 2005; 25: 9806 - 9819.
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