Product Datasheet
Thrombin Receptor Antibody
Catalog Number: 33500
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P25116
NCBI Gene ID: 2149
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human Thrombin Receptor.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CF2R; Coagulation factor II receptor; F2R; PAR-1; Proteinase activated receptor 1 precursor
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total Thrombin Receptor protein.
- Background:
- High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Vu T.-K.H., Cell 64:1057-1068(1991).
Kahn M.L., J. Clin. Invest. 103:879-887(1999).
Cargill M., Nat. Genet. 22:231-238(1999).
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