Product Datasheet  
S100 A1 Antibody  
Catalog Number: 33483  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P23297
    NCBI Gene ID: 6271
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human S100 A1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • S100-ALPHA ; S100 CALCIUM-BINDING PROTEIN A1;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total S100 A1 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

    Patrick Most, J. Biol. Chem., Nov 2003; 278: 48404 - 48412.
    Miki Okada, J. Biol. Chem., Feb 2004; 279: 4221 - 4233.
    Melanie Boerries, Mol. Cell. Biol., Jun 2007; 27: 4365 - 4373.
    Patrick Most, J. Clin. Invest., Dec 2004; 114: 1550 - 1563.




 
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