Product Datasheet
Osteopontin Antibody
Catalog Number: 33455
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P10451
NCBI Gene ID: 6696
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human osteopontin .
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Bone sialoprotein 1; Nephropontin; OPN; OSTP; SPP-1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total osteopontin protein.
- Background:
- Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity By similarity.
George R. Beck, J. Biol. Chem., Oct 2003; 278: 41921 - 41929.
KELLY L. HUDKINS, J. Am. Soc. Nephrol., Mar 1999; 10: 444.
L¨ªgia R. Rodrigues, Cancer Epidemiol. Biomarkers Prev., Jun 2007; 16: 1087 - 1097.
Yu-Hua Hsieh, Cancer Res., Jul 2006; 66: 7119 -
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