Product Datasheet  
NRF2 Antibody  
Catalog Number: 33450  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q16236
    NCBI Gene ID: 4780
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human NRF2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • HEBP1; NF-E2 related factor 2; NF2L2; NFE2-related factor 2; NFE2L2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total NRF2 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

    Rajesh K. Thimmulappa, J. Clin. Invest., Apr 2006; 116: 984 - 995.
    Sara B. Cullinan, Mol. Cell. Biol., Oct 2003; 23: 7198 - 7209.
    Tirumalai Rangasamy, J. Exp. Med., Jul 2005; 202: 47 - 59.
    Wenge Li, J. Biol. Chem., Aug 2005; 280: 28430 - 28438.




 
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