Product Datasheet  
NCK2 Antibody  
Catalog Number: 33447  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O43639
    NCBI Gene ID: 8440
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human NCK2.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Cytoplasmic protein NCK2; GRB4; NCK adaptor protein 2; NCKbeta; Nck-2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total NCK2 protein.
  • Applications：  
  • IHC
  • Background：  
  • Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.

    Susanne Frese, J. Biol. Chem., Jun 2006; 281: 18236 - 18245.
    Friedhelm Bladt, Mol. Cell. Biol., Jul 2003; 23: 4586 - 4597.
    Stephan J. Kempiak, J. Biol. Chem., Feb 2005; 280: 5836 - 5842.
    Min Chen, Mol. Cell. Biol., Nov 2000; 20: 7867 - 7880.



 
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