Product Datasheet  
MMP-16 Antibody  
Catalog Number: 33439  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P51512
    NCBI Gene ID: 4325
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human MMP-16 antibody.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • MMP-X2; MMPX2; MT-MMP 3; MT-MMP2; MT-MMP3
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total MMP-16 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform shortcleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.

    S. Simsa, J Anim Sci, Jun 2007; 85: 1393 - 1401.
    Dong-Jin Oh, Invest. Ophthalmol. Vis. Sci., Sep 2006; 47: 3887 - 3895.
    Amit Bar-Or, Brain, Dec 2003; 126: 2738 - 2749.
    Marco Seandel, Blood, Apr 2001; 97: 2323 - 2332.




 
© Signalway Biotechnology All Rights Reserved.