Product Datasheet
MART-1 Antibody
Catalog Number: 33429
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q16655
NCBI Gene ID: 2315
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human MART-1.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- MART-1; MART1; melan-A; MELAN A; MELANOMA ANTIGEN RECOGNIZED BY T CELLS 1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MART-1 protein.
- Background:
- Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Toshihiko Hoashi, J. Biol. Chem., Apr 2005; 280: 14006 - 14016.
Maria P. Bettinotti, J. Immunol., Jul 1998; 161: 877.
P. J. Frost, J. Immunol., Mar 2001; 166: 3564.
Flora Wang, Clin. Cancer Res., Oct 1999; 5: 2756.
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