Product Datasheet  
Keratin 16 Antibody  
Catalog Number: 33414  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P08779
    NCBI Gene ID: 3868
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human Keratin 16.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Keratin type I cytoskeletal 16; Cytokeratin-16; CK-16; K16;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Keratin 16 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

    Qian Wang, J. Virol., Jan 2004; 78: 821 - 833. RD Paladini,
    RD Paladini, J. Cell Biol., Feb 1996; 132: 381.
    M.K. Shamsher, Hum. Mol. Genet., Oct 1995; 4: 1875 - 1881.
    Ying-Nai Wang, Mol. Pharmacol., Jan 2006; 69: 85 - 98.



 
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