Product Datasheet
Keratin 15 Antibody
Catalog Number: 33413
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P19012
NCBI Gene ID: 3866
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human Keratin 15.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- Keratin type I cytoskeletal 15; Cytokeratin-15; CK-15; K15;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total Keratin 15 protein.
- Background:
- The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2.
F Smedts, Am. J. Pathol., Feb 1993; 142: 403.
RK Miller, J. Cell Biol., May 1991; 113: 843.
A Quaroni, J. Biol. Chem., Jun 1991; 266: 11923 - 11931.
AC Steven, J. Cell Biol., Dec 1983; 97: 1939.
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