Product Datasheet  
Dysferlin Antibody  
Catalog Number: 33360  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O75923
    NCBI Gene ID: 8291
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human Dysferlin.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • dysferlin; limb girdle muscular dystrophy 2B (autosomal recessive);
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Dysferlin protein.
  • Applications：  
  • WB
  • Background：  
  • Key calcium ion sensor involved in the Ca2+-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress By similarity.

    Delia J. Hern¨¢ndez-Deviez, Hum. Mol. Genet., Jan 2006; 15: 129 - 142.
    Yanchao Huang, FASEB J, Mar 2007; 21: 732 - 742.
    Mengfatt Ho, Hum. Mol. Genet., Sep 2004; 13: 1999 - 2010.
    Eriko Fujita, Hum. Mol. Genet., Mar 2007; 16: 618 - 629.



 
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