Product Datasheet  
DP-1 Antibody  
Catalog Number: 33359  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q14186
    NCBI Gene ID: 7027
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human DP-1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • E2F DIMERIZATION PARTNER 1; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTOR; SEQUENCE-SPECIFIC; DRTF1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total DP-1 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis.

    K Helin, Genes & Dev., Oct 1993; 7: 1850 - 1861.
    B Shan, Cell Growth Differ., Jun 1996; 7: 689.
    Hironori Ishida, J. Biol. Chem., Jul 2005; 280: 24642 - 24648.
    Wing Y. Chang, J. Biol. Chem., Dec 2004; 279: 51343 - 51353.



 
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