Product Datasheet
ARC Antibody
Catalog Number: 33325
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q5TZN6
NCBI Gene ID: 8996
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human ARC.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- Myp; NOL3; Nop30; Nucleolar protein 3; apoptosis repressor ARC
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ARC protein.
- Background:
- This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene.
Victor Ram¨ªrez-Amaya, J. Neurosci., Feb 2005; 25: 1761 - 1768.
Young-Jae Nam, J. Biol. Chem., Feb 2007; 282: 5522 - 5528.
Daryoush Ekhterae, Circ. Res., Dec 1999; 85: 70.
Tsai-Kun Li, Cancer Res., Dec 2003; 63: 8400 - 8407
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