Product Datasheet
CRMP-2 (Ab-522) Antibody
Catalog Number: 33317
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q16555
NCBI Gene ID: 1808
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human DPYSL2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP-2; CRMP2; DHPRP2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total DPYSL2 protein.
- Background:
- Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Goshima Y., Nature 376:509-514(1995).
Hamajima N., Gene 180:157-163(1996).
Kitamura K., DNA Res. 6:291-297(1999).
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