Product Datasheet  
53BP1 Antibody  
Catalog Number: 33297  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q12888
    NCBI Gene ID: 7158
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from Internal of human 53BP1.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • p53-binding protein 1; P531; TP53B; TP53BP1; TRP53BP1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total 53BP1 protein.
  • Applications：  
  • IHC
  • Background：  
  • Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

    Iwabuchi K., J. Biol. Chem. 273:26061-26068(1998).
    The German cDNA consortium; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
    Nakajima D., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.



 
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