Product Datasheet  
Mnk1 (Ab-385) Antibody  
Catalog Number: 33288  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9BUB5
    NCBI Gene ID: 8569
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human Mnk1 around the phosphorylation site of threonine 385 (L-P-T(p)-P-Q).
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • EC 2.7.11.1; kinase Mnk1; Map kinase interacting kinase; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Mnk1 protein.
  • Applications：  
  • WB
  • Background：  
  • May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

    Fukunaga R., EMBO J. 16:1921-1933(1997).
    Knauf U., Mol. Cell. Biol. 21:5500-5511(2001).
    O'Loghlen A., Exp. Cell Res. 299:343-355(2004).



 
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