Product Datasheet  
B-Raf (Ab-753) Antibody  
Catalog Number: 33277  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15056
    NCBI Gene ID: 673
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human B-Raf around the phosphorylation site of threonine 735 (P-K-T(p)-P-I).
  • reactivity：  
  • Hu Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • B-RAF; B-RAF proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase; BRAF; BRAF1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total B-Raf protein.
  • Applications：  
  • WB
  • Background：  
  • Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.

    Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).
    Hillier L.W., Nature 424:157-164(2003).
    Eychene A., Oncogene 7:1657-1660(1992).



 
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