Product Datasheet  
APLP2 (Ab-755) Antibody  
Catalog Number: 33274  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q06481
    NCBI Gene ID: 334
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human APLP2 around the phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y).
  • reactivity：  
  • Hu Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Amyloid protein homolog; Amyloid-like protein 2 precursor; APLP2; APP2; APPH
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total APLP2 protein.
  • Applications：  
  • WB
  • Background：  
  • May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity.

    Sprecher C.A., Biochemistry 32:4481-4486(1993).
    Wasco W., Nat. Genet. 5:95-99(1993).
    von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).



 
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