Product Datasheet  
iNOS (Ab-151) Antibody  
Catalog Number: 33261  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P35228
    NCBI Gene ID: 4843
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human iNOS around the phosphorylation site of tyrosine 151 (Q-Y-Y(p)-G-S).
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • EC 1.14.13.39; HEP-NOS; hepatocyte NOS; inducible NOS; nitric oxide synthase
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total iNOS protein.
  • Applications：  
  • WB
  • Background：  
  • Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

    Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993).
    Sherman P.A., Biochemistry 32:11600-11605(1993).
    Charles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993)



 
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