Product Datasheet
PKG2 (Ab-126) Antibody
Catalog Number: 33249
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q13237
NCBI Gene ID: 5593
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized non-phosphopeptide derived from human PKG2 around the phosphorylation site of serine 126 (G-V-S(p)-A-E).
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CGK 2; cGKII; cGMP-dependent protein kinase 2; EC 2.7.11.12; KGP2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PKG2 protein.
- Background:
- This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants.
Orstavik S., Biochem. Biophys. Res. Commun. 220:759-765(1996).
Fujii M., FEBS Lett. 375:263-267(1995).
Witczak O., Biochem. Biophys. Res. Commun. 245:113-119(1998).
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