Product Datasheet
MAP2K3 (Ab-222) Antibody
Catalog Number: 33236
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P46734
NCBI Gene ID: 5606
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized non-phosphopeptide derived from human MAP2K3 around the phosphorylation site of threonine 222 (A-K-T(p)-M-D).
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- dual specificity mitogen-activated protein kinase kinase 3; EC 2.7.12.2; kinase MKK3; MAP kinase kinase 3; MAP2K3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MAP2K3 protein
- Background:
- Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
Derijard B.,Science 267:682-685(1995).
The MGC Project Team;Genome Res. 14:2121-2127(2004).
Lim S.,J. Biol. Chem. 277:25040-25046(2002).
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