Product Datasheet
MAK (Ab-159) Antibody
Catalog Number: 33233
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P20794
NCBI Gene ID: 4117
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human MAK.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- EC 2.7.11.22; Male germ cell-associated kinase; Serine/threonine-protein kinase MAK;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MAK protein.
- Background:
- Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors By similarity. Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.
Mungall A.J., Nature 425:805-811(2003).
Matsushime H., Mol. Cell. Biol. 10:2261-2268(1990).
Greenman C., Nature 446:153-158(2007).
© Signalway Biotechnology All Rights Reserved.