Product Datasheet
MMP-1 Antibody
Catalog Number: 33434
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P03956
NCBI Gene ID: 4312
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human MMP-1 antibody.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CLGN; COLLAGENASE; FIBROBLAST; COLLAGENASE; INTERSTITIAL
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MMP-1 protein.
- Background:
- Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
Michael H. Pillinger, J. Biol. Chem., May 2007; 10.1074
Nick Di Girolamo, Invest. Ophthalmol. Vis. Sci., Nov 2003; 44: 4705.
Eiji Sunami, Oncologist, Apr 2000; 5: 108.
Christophe F. Deroanne, J. Cell Sci., Mar 2005; 118: 1173 - 1183.
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