Product Datasheet  
VAV1 (Ab-174) Antibody  
Catalog Number: 33208  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15498
    NCBI Gene ID: 7409
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Proto-oncogene vav; VAV1; VAV;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total VAV1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

    Ana V. Miletic, J. Biol. Chem., Dec 2006; 281: 38257 - 38265.
    Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003; 23: 6291 - 6299.
    Vered Schapira, Cancer Res., Jun 2006; 66: 6183 - 6191.
    Maya Groysman, J. Biol. Chem., Dec 2002; 277: 50121 - 50130.



 
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