Product Datasheet  
c-Jun (Ab-243) Antibody  
Catalog Number: 33194  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P05412
    NCBI Gene ID: 3725
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of serine 243.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Activator protein 1; AH119; AP-1; AP1; c-Jun
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total c-Jun protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

    Boyle W J, et al. (1991) Cell. 64(3): 573-584.
    Binetruy B, et al. (1991) Nature. 351: 122-127.
    Smeal T, et al. (1991) Nature. 354:494-496.
    Derijard B, et al. (1994) Cell. 76:1025-1037.
    Kyriakis J M, et al. (1994) Nature. 369: 156-160.



 
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