Product Datasheet  
CD253 Antibody  
Catalog Number: 33792  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P50591
    NCBI Gene ID: 8743
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human CD253.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

    Immunofluorescence: 1:100~1:500
  • other_names：  
  • Tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; Apo-2 ligand; Apo-2L
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CD253 protein.
  • Applications：  
  • WB IF
  • Background：  
  • Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

    Wiley S.R., Immunity 3:673-682(1995).
    Pitti R.M., J. Biol. Chem. 271:12687-12690(1996).
    Hymowitz S.G., Mol. Cell 4:563-571(1999).



 
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