Product Datasheet  
p73 Antibody  
Catalog Number: 33579  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O15350
    NCBI Gene ID: 7161
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human p73.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • p53-like transcription factor; p53-related protein; P73 alpha protein; p73-alpha; TP73
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total p73 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

    Kaghad M., Cell 90:809-819(1997).
    Mai M., Genomics 51:359-363(1998).
    De Laurenzi V., J. Exp. Med. 188:1763-1768(1998).




 
© Signalway Biotechnology All Rights Reserved.