Product Datasheet  
Histone H2A Antibody  
Catalog Number: 33265  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P0C0S8/P04908/P20671/Q96KK5/Q6FI13/Q7L7L0
    NCBI Gene ID: 8329/8332/8336/8969/3012/8335/3013/85235/723790/8337/92815
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from Internal of human Histone H2A.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • H2A.1b; H2A/c; H2A/d; H2A/i; H2A/n
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Histone H2A protein.
  • Applications：  
  • IHC
  • Background：  
  • Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Albig W., Hum. Genet. 101:284-294(1997).
    Albig W., Biol. Chem. 380:7-18(1999).
    Dobner T., DNA Seq. 1:409-413(1991).



 
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