Product Datasheet  
ITGB4 (Ab-1510) Antibody  
Catalog Number: 33169  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P16144
    NCBI Gene ID: 3691
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • CD104 antigen; GP150; ITB4; integrin beta-4; integrin beta-4C
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ITGB4 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.

    Suzuki S., EMBO J. 9:757-763(1990).
    Hogervorst F., EMBO J. 9:765-770(1990).
    Tamura R.N., J. Cell Biol. 111:1593-1604(1990).



 
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