Product Datasheet  
PKA-R2β (Ab-113) Antibody  
Catalog Number: 33161  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P31323
    NCBI Gene ID: 5577
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human PKA-R2β around the phosphorylation site of serine 113 (R-A-S(p)-V-C).
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • KAP3; PKA R2-beta; PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory chain;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total PKA-R2β protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

    Levy F.O., Mol. Endocrinol. 2:1364-1373(1988).
    Ota T., Nat. Genet. 36:40-45(2004).
    Scherer S.W., Science 300:767-772(2003)



 
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