Product Datasheet  
SF1 (Ab-82) Antibody  
Catalog Number: 33142  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q15637
    NCBI Gene ID: 7536
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human SF1 around the phosphorylation site of serine 82 (S-P-S(p)-P-E).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • BBP; CW17; Mammalian branch point binding protein mBBP; SF01; Splicing factor 1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total SF1 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.

    Susan Y. Park, Development, May 2005; 132: 2415 - 2423.
    Dujin Zhou, Mol. Endocrinol., Jul 2000; 14: 986.
    Dagmar Wilhelm, Genes & Dev., Jul 2002; 16: 1839.
    Philipp Gut,Development, Oct 2005; 132: 4611 - 4619.



 
© Signalway Biotechnology All Rights Reserved.