Product Datasheet  
NRP1 Antibody  
Catalog Number: 33113  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:O14786
    NCBI Gene ID:8829
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein of human NRP1.
  • reactivity:  
  • Human,Mouse,Rat
  • appl_detail:  
  • WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • other_names:  
  • NP1; NRP; BDCA4; CD304; VEGF165R
  • Purification:  
  • Antibodies were purified by affinity purification using immunogen.
  • Specificity:  
  • The antibody detects endogenous level of total NRP1 protein.
  • Applications:  
  • WB,IF
  • Background:  
  • This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.



 
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