Product Datasheet  
MECOM Antibody  
Catalog Number: 32966  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q13465
    NCBI Gene ID:2122
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein of human MECOM.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:500 - 1:2000
    Immunohistochemistry: 1:50 - 1:200

  • other_names：  
  • EVI1; MDS1; PRDM3; MDS1-EVI1; AML1-EVI-1
  • Purification：  
  • Antibodies were purified by affinity purification using immunogen.
  • Specificity：  
  • The antibody detects endogenous level of total MECOM protein.
  • Applications：  
  • WB IHC
  • Background：  

  • The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.




 
© Signalway Biotechnology All Rights Reserved.