Product Datasheet
CPE Antibody
Catalog Number: 32861
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P16870
NCBI Gene ID:1363
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Recombinant protein of human CPE.
- appl_detail:
- WB 1:500 - 1:2000
IF 1:50 - 1:200
- other_names:
- CarboxypeptidaseE; CarboxypeptidaseH; CPE; CPH; Enkephalinconvertase
- Purification:
- Antibodies were purified by affinity purification using immunogen.
- Specificity:
- The antibody detects endogenous level of total CPE protein.
- Background:
- This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
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