Product Datasheet  
ATL1 Antibody  
Catalog Number: 32756  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q8WXF7
    NCBI Gene ID:51062
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein of human ATL1.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500 - 1:2000
    Immunohistochemistry: 1:50 - 1:200
    Immunofluorescence: 1:50 - 1:200
  • other_names:  
  • FSP1; GBP3; SPG3; HSN1D; SPG3A
  • Purification:  
  • Antibodies were purified by affinity purification using immunogen.
  • Specificity:  
  • The antibody detects endogenous level of total ATL1 protein.
  • Applications:  
  • WB IHC IF
  • Background:  
  • The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.



 
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