Product Datasheet  
GADD45A Antibody  
Catalog Number: 32438  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P24522
    NCBI Gene ID:1647
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein of human GADD45A.
  • reactivity:  
  • Human,Mouse,Rat
  • appl_detail:  
  • WB 1:500 - 1:2000
  • other_names:  
  • DDIT1; GADD45;
  • Purification:  
  • Antibodies were purified by affinity purification using immunogen.
  • Specificity:  
  • The antibody detects endogenous level of total GADD45A protein.
  • Applications:  
  • WB,IHC,IF
  • Background:  
  • This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.




 
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