Product Datasheet  
ISCU antibody  
Catalog Number: 31981  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9Y3B1
    NCBI Protein#: BC011906
  • Form of Antibody：  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein of human ISCU
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB dilution:1:500-1:2000
  • other_names：  
  • HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.



 
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