Product Datasheet
IL34 antibody
Catalog Number: 31957
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NPI7
NCBI Gene ID: NP_001166243
- Form of Antibody:
- pH7.4 PBS, 0.05% NaN3, 40% Glycerol
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide of human IL34
- appl_detail:
- WB dilution:1:200-1:1000
IHC dilution:1:30-1:150
- other_names:
- IL-34; C16orf77
- Purification:
- Antigen affinity purification
- Background:
- Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
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