Product Datasheet
GUCA1A antibody
Catalog Number: 31880
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14944
NCBI Protein#: BC031663
- Form of Antibody:
- pH7.4 PBS, 0.05% NaN3, 40% Glycerol
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein of human GUCA1A
- appl_detail:
IHC dilution:1:50-1:100
- other_names:
- COD3; GCAP; GUCA; GCAP1; GUCA1; CORD14; C6orf131
- Purification:
- Antigen affinity purification
- Background:
- This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants.
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