Product Datasheet  
DUSP7 antibody  
Catalog Number: 31861  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q14689
    NCBI Protein#: BC019107
  • Form of Antibody：  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein of human DUSP7
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  

  • IHC dilution:1:50-1:300
  • other_names：  
  • MKPX; PYST2
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • Applications：  
  • IHC
  • Background：  
  • Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).



 
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