Product Datasheet  
FBH1 antibody  
Catalog Number: 31855  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: O00148
    NCBI Protein#: BC032674
  • Form of Antibody:  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Fusion protein of human FBH1
  • reactivity:  
  • Hu, Ms
  • appl_detail:  

  • IHC dilution:1:100-1:300
  • other_names:  
  • Fbx18; hFBH1; FBXO18
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • Applications:  
  • IHC
  • Background:  
  • This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.



 
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