Product Datasheet  
cbx7 Antibody  
Catalog Number: 31805  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O95931
    NCBI Gene ID: 23492
    NCBI mRNA#: NM_175709.4
    NCBI Protein#:NP_783640.1
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20�?1 year
  • Immunogen：  
  • A synthesized peptide derived from human cbx7,corresponding to a region within N-terminal amino acids.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • WB dilution: 1:500-1:2000

    IF dilution: 1:100-1:500

  • other_names：  
  • Cbx 7; CBX7; Chromobox homolog 7; Chromobox protein homolog 7;
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB IF
  • Background：  

  • Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.




 
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