Product Datasheet
MICB Polyclonal Antibody
Catalog Number: 31739
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q29980
NCBI Gene ID:4277
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human MICB (NP_005922.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- MICB; PERB11.2; MHC class I polypeptide-related sequence B
- Purification:
- Affinity purification
- Background:
- This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
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