Product Datasheet
MYL12A Polyclonal Antibody
Catalog Number: 31678
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P19105
NCBI Gene ID:10627
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human MYL12A (NP_006462.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- MYL12A; HEL-S-24; MLC-2B; MLCB; MRCL3; MRLC3; MYL2B; myosin light chain 12A
- Purification:
- Affinity purification
- Background:
- This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
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