Product Datasheet
MGAT2 Polyclonal Antibody
Catalog Number: 31674
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q10469
NCBI Gene ID:4247
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human MGAT2 (NP_002399.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:200 - 1:2000
IHC 1:50 - 1:200
- other_names:
- MGAT2; CDG2A; CDGS2; GLCNACTII; GNT-II; GNT2; alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Purification:
- Affinity purification
- Background:
- The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.
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