Product Datasheet
SPO11 Polyclonal Antibody
Catalog Number: 31668
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y5K1
NCBI Gene ID:23626
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human SPO11 (NP_937998.1).
- appl_detail:
- WB 1:200 - 1:2000
- other_names:
- SPO11; CT35; SPATA43; TOPVIA; meiotic recombination protein SPO11
- Purification:
- Affinity purification
- Background:
- Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
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