Product Datasheet
ERBB2IP Polyclonal Antibody
Catalog Number: 31608
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96RT1
NCBI Gene ID:55914
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human ERBB2IP (NP_061165.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- ERBIN; ERBB2IP; HEL-S-78; LAP2; erbin
- Purification:
- Affinity purification
- Background:
- This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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