Product Datasheet
SLC12A5 antibody
Catalog Number: 31967
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N108
NCBI Gene ID: NP_001128243
- Form of Antibody:
- pH7.4 PBS, 0.05% NaN3, 40% Glycerol
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide of human SLC12A5
- appl_detail:
IHC dilution:1:30-1:150
- other_names:
- KCC2; EIG14; hKCC2; EIEE34
- Purification:
- Antigen affinity purification
- Background:
- K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.
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